Present review article was made to throw light on importance of pesticides in food. This review was collected all researches related to pesticides and food during last twenty years. These articles were collected from Googleschloar, Pubmed and other research web portals and meta analysis was done to understand the concept more thoroughly under every spectrum. It was found that on one hand, pesticides are beneficial to improve crop yield by destroying harmful pests, insects and weeds, simultaneously on other hand, these put many harmful effect on human health in the form of cancers of many types, parkinsonism, Alzheimer’s etc. Besides this, in children, side effects of autism and hyperactivity syndrome were also noticed. Organic pesticides showed lesser side effects in comparison to synthetic pesticides. There is further need to invent more effective technology with lesser or no side effects.